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Laurence J. Hyman 

Of Counsel

Before joining canady + lortz, Larry Hyman was a partner in the Biotechnology and Chemistry Practice Group  at Townsend and Townsend and Crew, LLP, a national, IP-focused firm (now part of Kilpatrick Townsend & Stockton LLP).  Prior to joining Townsend, Mr. Hyman practiced for more than 5 years at the National Institutes of Health's Office of Technology Transfer, where he was the lead patent advisor for the General Medicine Workgroup. 

Mr. Hyman focuses his practice on biotechnology patenting, strategic planning and counseling, technology licensing, intellectual property due diligence, patent portfolio evaluations, and portfolio management.  Mr. Hyman also advises clients on compliance with reporting requirements for research conducted under federal funding.  Mr. Hyman has represented a wide variety of clients, including the U.S. Government, academic institutions, start-up and medium sized biotechnology and drug discovery companies, venture capital groups, and pharmaceutical companies.  He serves as a reviewer of grant applications on therapeutics, diagnostics, and devices for the University of California, San Francisco, Clinical and Translational Science Institute, mentors a class on IP Due Diligence for Life Sciences, and has lectured on patent law at Golden Gate University.  He also serves as a consultant on biotechnology patent matters to the Gerson Lehrman Group expert network.  Mr. Hyman was recognized as a 2011 "Top Patent Prosecutor for Pharmaceuticals/Biotechnology" by the patent analytics website PatentBuddy.com.  

Mr. Hyman's patent and licensing work has encompassed biologics (particularly antibody- and cytokine-based targeted therapeutics), protein chemistry, biochemistry, molecular biology, RNA interference, immunology, human and animal vaccines, plant biology, agricultural methods and compositions, transgenic plants and bacteria, biofuels, personalized medicine, enzymology, nanotechnology, stem cells, food coatings and processing, drug administration, high throughput screening, water purification, imaging methods, radiation administration, and microfluidic and medical devices.

Education

Georgetown University, M.S., Biology.

Boston University School of Law, J.D.

The University of Chicago, A.B., Biological Sciences.

Bar Admissions

California

New York

Massachusetts (voluntarily on inactive status)

District of Columbia (voluntarily on inactive status)

U.S. Supreme Court

U.S. Court of Appeals for the D.C. Circuit

U.S. Court of Appeals for the Federal Circuit

Registered patent attorney, U.S. Patent and Trademark Office

Memberships

American Bar Association, Intellectual Property Law Section

American Intellectual Property Law Association

Association of University Technology Managers

State Bar of California, Intellectual Property Section

Patent Experience       

The following are U.S. patents which have issued on applications written by Laurence J. Hyman, most of which were also prosecuted by him in whole or in part.  
             
U.S. Patent No.  8,263,651.  Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to treat conditions mediated by PBR, CB2, and NK2 receptors.
U.S. Patent No.  8,242,170.  Use of cis-epoxyeicosatrienoic acids and inhibitors of soluble epoxide hydrolase to reduce cardiomyopathy 
U.S. Patent No. 8,198,063.  Rapid deglycosylation of glycoproteins.
U.S. Patent No. 8,124,085.  Bispecific binding agents for modulating biological activity.
U.S. Patent No. 8,084,220.  Methods for detecting the presence of expanded CGG repeats in the FMR1 gene 5' untranslated region.
U.S. Patent No. 8,039,593.  Antibodies and immunotoxins that target human glycoprotein NMB.
U.S. Patent No. 7,982,011.  Mutated anti-CD22 antibodies and immunoconjugates.
U.S. Patent No. 7,968,298.  Use of herpesviruses, herpesvirus proteins and nucleic acids encoding the proteins to inhibit CCR5-tropic HIV-1 infection and replication.
U.S. Patent No. 7,951,831.  Use of inhibitors of soluble epoxide hydrolase to synergize activity of COX and 5-LOX inhibitors.
U.S. Patent No. 7,927,635.  Nematicides from Juglandaceae and methods of use thereof.
U.S. Patent No. 7,855,053.  Methods for detecting the presence of expanded CGG repeats in the FMR1 gene 5' untranslated region.
U.S. Patent No. 7,777,019.  Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells.
U.S. Patent No. 7,691,630.  Compositions for protecting plants from pathogens.
U.S. Patent No. 7,666,591.  Single stranded DNA binding proteins from Archaea and uses therefor.
U.S. Patent No. 7,541,040.  Chimeric molecule for the treatment of TH2-like cytokine mediated disorders.   
U.S. Patent No. 7,521,054.  Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the Fv to lower the isoelectric point.
U.S. Patent No. 7,517,849.  Inhibition of ABC transporters by transmembrane domain analogs.
U.S. Patent No. 7,470,775.  Anti-CD30 stalk and anti-CD30 antibodies suitable for use in immunotoxins.
U.S. Patent No. 7,404,954.  Methods of targeting agents to cells expressing the polymeric immunoglobulin receptor.
U.S. Patent No. 7,399,827.  Page-4, an x-linked gage-like gene expressed in normal and neoplastic prostate, testis and uterus, and uses therefor.
U.S. Patent No. 7,368,110.  Antibodies, including Fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use.
U.S. Patent No. 7,355,012.  Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells.
U.S. Patent No. 7,193,054.  Nanofabrication using actin filaments.
U.S. Patent No. 7,129,332.  Anti-EGFRvIII scFvs with improved cytotoxicity and yield, immunotoxins based thereon, and methods of use thereof.
U.S. Patent No. 7,081,518.  Anti-mesothelin antibodies having high binding affinity.
U.S. Patent No. 7,060,486.  Inhibition of sulfate-reducing-bacteria-mediated degradation using bacteria which secrete antimicrobials.   
U.S. Patent No. 7,052,911.  Methods of increasing plant yield.
U.S. Patent No. 7,052,703.  T-cell receptor gamma alternate reading frame protein (TARP), and uses thereof. 
U.S. Patent No. 6,905,822.  Methods of diagnosing multidrug resistant tuberculosis.
U.S. Patent No. 6,869,628.  Methods and formulations for providing gloss coatings to foods and for protecting nuts from rancidity.
U.S. Patent No. 6,855,810.  Ligands directed to the non-secretory component, non-stalk region of plgR and methods of use thereof.
U.S. Patent No. 6,852,832.  Single stranded DNA binding proteins from archaea.
U.S. Patent No. 6,720,167.  Insecticidal bacteria, and methods for making and using them.
U.S. Patent No. 6,696,064.  Methods of protecting vasculature from damage by diphtheria toxin-and pseudomonas toxin-based immunotoxins during therapy.
U.S. Patent No. 6,630,197.  Inhibition of sulfate-reducing-bacteria-mediated degradation using bacteria which secrete antimicrobials.
U.S. Patent No. 6,582,961.  Methods of protecting plants from pathogens. 
U.S. Patent No. 6,570,069.  Nucleic acids encoding plant inhibitors of apoptosis and transgenic cells and plants expressing them.  
U.S. Patent No. 6,511,824.  Selective assay for determining the identity of live microorganisms in a mixed culture.
U.S. Patent No. 6,402,914.  In-situ loader for electrophoretic gels.
U.S. Patent No. 6,191,103.  Methods for enhancing thrombolysis in a mammal.


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